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Product Name: Factory Supply 99% CAS 15307-79-6 Diclofenac Sodium Model NO.: 15307-79-6 Purity: >99% State: Solid Suitable for: Adult Certification: GMP Customized: Non-Customized Powder: Yes Sample: Ok Shipping: by Air, by Sea Name: Diclofenac Sodium CAS: 15307-79-6 Keywords: Diclofenac Sodium Other Name: Diclofenac Sodium Trademark: crovell Transport Package: Bags Specification: white crystals powder Origin: China HS Code: 3001909010 Product Description 99% CAS 15307-79-6 Diclofenac Sodium detailsDescription ofDiclofenac SodiumDiclofenac Sodium is the salt form of diclofenac, an active metabolite of the NSAID aceclofenac (sc-217557). Hydrolysis ofaceclofenac, an inhibitor of interleukin-1B-induced prostaglandin E2 production with no inhibitory activity against Cox(cyclooxygenase), generates diclofenac, an inhibitor of both Cox-1 and Cox-2. Oxidation of diclofenac produces the metabolite 4'-hydroxy diclofenac (sc-202423) which demonstrates specific inhibition of Cox-2. Inhibition of Cox by diclofenac and 4'-hydroxy diclofenac suppresses prostaglandin E2 synthesis, producing antiinflammatory and analgesic effects. Diclofenac is alsoshown to stabilize the native tetrameric conformation of transthyretin (TTR) fibrils, preventing the formation of insolubleamyloidogenic TTR deposits. Diclofenac Sodium is a substrate of CYP2C9.Specification ofDiclofenac SodiumCharacteristicsWhite crystalline powderSolubility:Sparingly soluble in water, freely soluble in methanol, ethanol(96%);slightly soluble in acetone; practically insoluble in ether.,Melting point275-277Related Substances:Single impurity max 0.2%total impurity max 0.5%Heavy metal:Max 10ppmLoss on dryingMax 0.5%Assay:99.0-101.0%Picture for theDiclofenac SodiumFunction1. Relieve rheumatoid arthritis and osteoarthritis. Acute exacerbation of osteoarthritis of the spine, gouty arthritis, rheumatoid arthritis, or persistent joint swelling and pain;2. kinds of soft tissue, such as rheumatic pain, shoulder pain, tenosynovitis, bursitis and myalgia after exercise injury pain;3, acute mild and moderate pain, such as: surgery, trauma, strain and other pain;4, primary dysmenorrhea, toothache, headache, etc.package and shipping[Storage]Storedinaclean,coolanddryarea;keepawayfromstrong,directlight.[ShelfLife]2yearswhenproperlystored.[Packing]Innerdoubleplasticbags--25kg/Fiberdrum(35*35*53cm,GW:28kg,NW:25kg,0.06CBM);Innerdoubleplasticbags--5kg/Aluminumfoilbag(GW:6.5kg,NW:5kg);Innerdoubleplasticbags--1kg/Aluminumfoilbag(GW:1.5kg,NW:1kg).[Delivery]5workingdaysafterpayment.Shipping1.PreferentiallyDHLorFedExforquantitylessthan50KG;Airshippingfor100KGabove;Seashippingforquantityover500KG.Company informationThanks for your considering of Crovell Biotech (Hebei) Co., Ltd.(Guanlang). Crovell is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.Crovell is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., Crovell also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.After ten years development,Crovell has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.So far, Crovell has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,Crovell can always make the product quality best, some of the products from Crovell can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing Crovell.In future, Crovell must become to a more important trade bridge for china and foreign countries especially in pharmaceutical industries.Contact us
